Chronic rhinosinusitis

Summary about Disease


Chronic rhinosinusitis (CRS) is a long-term inflammation of the sinuses and nasal passages. It's characterized by persistent symptoms such as nasal congestion, facial pain/pressure, and a reduced sense of smell, lasting for 12 weeks or longer, despite attempts at treatment. It can significantly impact a person's quality of life.

Symptoms


Nasal congestion or blockage

Facial pain, pressure, or fullness

Nasal discharge (runny nose), often thick and discolored

Postnasal drip (mucus dripping down the back of the throat)

Reduced sense of smell (hyposmia) or loss of smell (anosmia)

Cough

Fatigue

Headache

Ear pain, pressure, or fullness

Upper tooth pain

Causes


CRS is often multifactorial, meaning several factors contribute to its development. Some common causes include:

Nasal polyps: Soft, noncancerous growths in the nasal passages or sinuses.

Deviated nasal septum: A crooked septum can block sinus passages.

Allergies: Allergic reactions can cause inflammation in the sinuses.

Respiratory infections: Viruses and bacteria can lead to sinus inflammation.

Immune system disorders: Conditions that weaken the immune system.

Fungal infections: In some cases, fungi can cause chronic sinusitis.

Environmental factors: Air pollution, cigarette smoke, and other irritants.

Medicine Used


Nasal corticosteroids: Sprays to reduce inflammation (e.g., fluticasone, mometasone).

Saline nasal irrigation: Rinsing the nasal passages with salt water to clear mucus.

Oral corticosteroids: Pills for short-term use in severe cases to reduce inflammation (e.g., prednisone).

Antibiotics: Used when a bacterial infection is suspected.

Antifungal medications: Used in cases of fungal sinusitis.

Decongestants: To relieve nasal congestion (use with caution and not for long-term).

Antihistamines: If allergies are a contributing factor.

Leukotriene inhibitors: Help reduce inflammation (e.g., montelukast).

Biologics: In severe cases, medications that target specific inflammatory pathways (e.g., dupilumab).

Is Communicable


Chronic rhinosinusitis itself is not communicable. It is an inflammatory condition and not caused by a contagious agent. However, if an acute respiratory infection (like a cold or flu) triggers or exacerbates CRS symptoms, the infection itself might be communicable during the acute phase.

Precautions


Avoid irritants: Limit exposure to smoke, pollutants, and allergens.

Practice good hygiene: Wash hands frequently to prevent respiratory infections.

Use a humidifier: To keep nasal passages moist, especially in dry climates.

Manage allergies: Avoid known allergens and follow allergy treatment plans.

Stay hydrated: Drink plenty of fluids to thin mucus.

Quit smoking: Smoking irritates the nasal passages and sinuses.

How long does an outbreak last?


CRS is a chronic condition, meaning it's ongoing. Therefore, it doesn't have "outbreaks" in the same way as an acute infection. Symptoms persist for at least 12 weeks. There might be periods of worsening symptoms (exacerbations or flare-ups), followed by periods of relative improvement, but the underlying inflammation remains.

How is it diagnosed?


Diagnosis typically involves:

Medical history: Discussion of symptoms and past medical conditions.

Physical examination: Examination of the nose and throat.

Nasal endoscopy: Using a thin, flexible tube with a camera to visualize the nasal passages and sinuses.

CT scan: Imaging test to evaluate the sinuses for inflammation, blockages, or structural abnormalities.

Allergy testing: To identify potential allergic triggers.

Nasal cultures: If a bacterial or fungal infection is suspected.

Timeline of Symptoms


CRS is defined by symptoms lasting for at least 12 weeks (3 months). While symptoms may fluctuate in severity, they are persistently present for this duration. It's not characterized by a sudden onset and resolution but rather by a chronic inflammatory process.

Important Considerations


Seek medical care: It is important to see a doctor for proper diagnosis and treatment to improve your quality of life.

Adherence to treatment: Consistent use of prescribed medications and therapies is crucial for managing CRS.

Underlying conditions: Rule out and manage underlying conditions like allergies, asthma, or immune deficiencies that can contribute to CRS.

Surgical options: Surgery may be considered for severe cases that don't respond to medical treatment.

Lifestyle modifications: Implementing preventive measures can help minimize symptom flare-ups.